Liver disease encompasses a broad spectrum of conditions, ranging from mild abnormalities in liver enzyme levels to severe cirrhosis or liver failure. In the context of Cyproterone usage, the liver plays a crucial role in metabolizing the medication and clearing it from the body. However, in individuals with liver disease, impaired liver function can affect the body’s ability to process and eliminate Cyproterone effectively.
Cyproterone has been associated with hepatotoxicity, meaning it can potentially damage liver cells and worsen existing liver conditions. As a result, individuals with liver disease, or abnormal liver function tests, are advised against using Cyproterone as part of their gender-affirming care. Administrating Cyproterone to such individuals could exacerbate liver damage, leading to adverse health outcomes and complications.
Alternative medications, such as spironolactone or GnRH agonists, are considered to be safer alternatives in individuals with liver disease.
Cyproterone and Liver Disease: Understanding the Potential Risks
Monitoring Liver Enzymes in those Wishing to Take Cyproterone as their Antiandrogen