Cyproterone Acetate

Cyproterone acetate is a medication used in gender-affirming hormone therapy to reduce the effects of testosterone for trans women and non-some binary people. It can help decrease facial and body hair growth, lower libido, and reduce spontaneous erections. #


Cyproterone acetate is usually available in tablet form and usually costs £10-£40 a month. Common strengths include 10 mg, 50 mg, or 100 mg tablets, depending on the prescribing guidelines in your region.


Possible Side Effects

Most people tolerate cyproterone acetate well, but side effects can include:

Common

  • Tiredness or low energy

  • Lower libido

  • Mood changes

  • Weight changes

Less common

  • Changes in liver function

  • Changes in mood or mental health

  • Breast tenderness

  • Reduced fertility (possibly long-term)


Monitoring

Cyproterone acetate can affect liver function, and so isn't appropriate for anyone with liver impairment. Liver function blood tests are needed both before starting on cyproterone acetate, and every three months while you're taking it. You can read about essential blood tests here.