Maintaining hormone levels within the target range is important for both safety and effectiveness. When hormone levels are too low the body may not receive the intended physical, emotional, or metabolic benefits. This applies to anyone on hormone therapy: trans men, women, and nonbinary people.
Potential Risks
For Transfeminine Patients
Incomplete feminization: this means slower or limited changes in fat redistribution, breast growth, and skin softening.
Bone density loss: oestrogen is protective for bone density; low levels increase the risk of osteopenia or osteoporosis.
Mood changes: low oestrogen can be associated with mood changes, fatigue, and low energy.
Read about transfeminine hormone target ranges here.
For Transmasculine Patients (Testosterone Therapy)
Incomplete masculinization: reduced muscle development, body hair growth, and voice changes.
Menstrual return: insufficient testosterone may not fully suppress menstruation.
Bone density loss: low testosterone can contribute to weaker bones over time.
Mood changes: low levels may contribute to irritability, fatigue, or depressive symptoms.
Read about transmasculine target ranges here.
General Risks of Low Hormone Levels
Cardiovascular health: low hormone levels can increase cholesterol, blood pressure, and heart attack risk.
Sexual health: decreased libido and sexual dysfunction can occur in both transfeminine and transmasculine patients.
Quality of life: persistent fatigue, low motivation, and reduced sense of well-being are commonly reported.
Monitoring Matters
Regular blood testing and Transition Pack reviews ensure hormone levels remain in a safe and effective range. Skipping doses, insufficient doses or inconsistent use can all lead to the above unwanted effects.
What to Do
If you experience symptoms that suggest your hormone levels may be too low, book a blood test and share the results with us by submitting a Transition Pack Request. Adjustments to dosage, timing, or medication type can often resolve the issue.