Choosing an Oestrogen Blocker

Leuprorelin (Prostap®)

  • Costs £270-£300 a month.
  • This is administered as either an intramuscular or subcutaneous injection every 4 to 12 weeks.
  • It works by suppressing the production of the hormone GnRH, which results in the suppression of the production of oestrogen and testosterone.
  • It has been established as safe and well-tolerated, with very few side effects.


Triptorelin (Decapeptyl®)

  • Costs £270-£300 a month.
  • This is administered as an intramuscular injection every 10 to 14 weeks.
  • It works by suppressing the production of the hormone GnRH, which results in the suppression of the production of oestrogen and testosterone.
  • It has been established as safe and well-tolerated, with very few side effects.


Nafarelin (Synarel®)

  • Costs £70-£100 a month.
  • This is administered as a nasal spray that is taken twice a day.
  • It works by suppressing the production of the hormone GnRH, which results in the suppression of the production of oestrogen and testosterone.
  • It has been established as safe and well-tolerated, with very few side effects.


Raloxifene

  • Costs £6-£14 a month.
  • Taken as a tablet.
  • A SERM, it works by modulating oestrogen receptor activity, particularly in the breasts, reducing breast size.
  • It has been established as safe and well-tolerated, with very few side effects.