Which antiandrogen / testosterone blocker should I take?

Which antiandrogen / testosterone blocker should I take?

The best blockers are the GnRHa medications which can be taken as a nasal spray or an injection but they are expensive if you're funding them yourself.

If your funds are limited and you're trying to reduce the effects of testosterone, finasteride is the simplest and safest option (but maybe not the most effective).

Spironolactone and cyproterone are probably equally effective but require you to have more blood tests. Bicalutamide is no longer recommended because of the risks of liver toxicity.


    • Related Articles

    • How can I take things slowly?

      Many people want to take things slowly for whatever reason, and that's absolutely fine. You can start on a small dose of hormones, with or without a blocker. But remember that our bodies do need hormones so if you are blocking your natural hormone ...
    • Do I need a blocker if I am masculinising?

      If you can afford it, the GnRHA nasal spray or blockers are very good at suppressing the ovaries and stopping them from producing estrogen. However, if funds are limited, testosterone is often enough (with time) to suppress the ovaries, stop periods, ...
    • How long will a blocker last? When will it run out?

      There's no exact timeframe available. Like many things, this varies according to the individual. Current evidence suggests a blocker injection can last anywhere between three months and two years.
    • Will testosterone stop my periods?

      Yes, one of the effects of testosterone masculinising therapy is menstrual suppression. Most people find that their periods stop within 1–6 months of starting testosterone therapy, depending on the dose and individual response. However, it’s ...
    • Is it safe to take Hormone Replacement Therapy (HRT)?

      Switching your hormone profile from one to the other is surprisingly safe. If you're switching to an estrogen profile, you'll have the same chance of developing illnesses that someone who was assigned female at birth will have. If you're switching to ...