What is Progesterone?
Progesterone is a naturally occurring hormone found in both cisgender (non-transgender) and transgender individuals. In the context of gender-affirming care, progesterone may be prescribed to transgender women and individuals assigned male at birth (AMAB) to help promote feminising physical characteristics and align their external appearance with their gender identity.

How Does Progesterone Work?
Progesterone is one of the hormones involved in regulating the menstrual cycle and pregnancy in cisgender women. In gender-affirming care, it is used to complement estrogen therapy to enhance certain feminising effects.

Using Progesterone for Gender-Affirming Care:
For transgender women and AMAB individuals seeking feminisation, progesterone therapy can be a component of their gender-affirming journey. The goal is to develop a more feminine appearance and alleviate gender dysphoria.

Administration of Progesterone:
Progesterone can be administered in various forms, including oral tablets, vaginal or rectal tablets and topical creams. The choice of administration method depends on individual preferences, medical considerations, and expert recommendations.

Potential Changes and Effects of Progesterone:
The introduction of progesterone into the body may lead to various physical and emotional changes over time, including:

• Development of breast tissue
• Softening of the skin
• Changes in mood and emotions
• Possible changes in libido

It’s important to note that the feminising effects of progesterone can vary among individuals, and not everyone may experience the same results.

Dosage and Monitoring:
The dosage of progesterone and the frequency of administration will be determined by your healthcare provider based on your specific needs and goals. Regular monitoring of hormone levels and overall health is essential to ensure the safe and effective use of progesterone.

Potential Side Effects and Considerations:
While progesterone therapy is generally safe, it may be associated with some side effects as seen in cisgender women, including:

• Mood swings or emotional changes
• Breast tenderness
• Changes in appetite and weight

Be sure to discuss any concerns or side effects during your treatment.

Conclusion:
Progesterone can be a valuable component of gender-affirming care for transgender women and AMAB individuals seeking feminisation. It may help enhance certain physical changes that align with one’s gender identity.

Always maintain open communication regarding your goals, concerns, and any side effects you may experience during your hormone therapy journey.

For any questions or concerns about progesterone therapy or your gender-affirming care, consult your healthcare provider for personalised guidance and support.

[Disclaimer: This information is for educational purposes only and should not replace professional medical advice. Please consult a doctor for personalised recommendations and treatment plans.]